Next Generation iCIEF

CEInfinite Imaged Capillary Isoelectric Focusing (iCIEF) Solutions

Isogen Life Science is the exclusive distributor of the CEInfinite Imaged Capillary Isoelectric Focusing (iCIEF) product line from AES (Advanced Electrophoresis Solutions Ltd). Since 2004 our company has been the Total CIEF Solution Provider for any (i)CIEF assays, supporting and delivering the Total CIEF Solutions to the European market.

For CE Solutions we offer the CAPEL Capillary Electrophoresis (CE) instruments.

 

Contact us for a demo opportunity  

Scroll Down Vector Art, Icons, and Graphics for Free Download

The CEInfinite is a new generation WCTID CIEF system, standard equipped with a high sensitivity CMOS imaging sensor and powerful deep UV LED light source. CEInfinite dramatically increases the scan rate over 100 times compared to any other imaging time-resolved CIEF systems. It enables the study of fast dynamic processes more accurately, empowering Taylor dispersion rapid measurement of protein hydrodynamic radius, and protein interaction studies. Furthermore, it is the only WCTID CIEF system that enables you to perform direct coupling to MS for in depth characterisation studies and high resolution iCIEF fractionation for further studies like peptide mapping, SPR and biological assays.

CEInfinite iCIEF solutions provides you:

  • iCIEF faster method development, higher detection sensitivity, better reliability and higher analytical throughput
  • iCIEF automated high-resolution fractionation
  • iCIEF-MS, coupling with mass spectrometry  
  • Method development services - we can perform your method development of any (i)CIEF assays
  • High resolution fractionation services - we can fractionise your samples  
  • A comprehensive portfolio of carrier ampholytes, pI markers, cartridges and solutions for any i(CIEF) assays

We will help you out and provide you the best services that you need. We understand your needs. 
Meet the Experts, Join our Team, Together, we can make it happen.

Contact us for any question, let's discuss it together!

Save time with our NEW CEInfinite Essential iCIEF System (Model M)

Our new CEInfinite Essential iCIEF instrument is equipped with a manual injection system. Therefore, it offers you:

  • High-resolution
  • High-throughput
  • Less time
  • Less resources

From now onwards, you can accelerate your project with simple workflows with our new Model M. It can be applied in fields like pharmaceutical, agricultural, environmental sciences, and many more.

CEInfinite Essential iCIEF Advantages

  • Fast sample injection < 1 min
  • Minimum sample injection of 2 μL
  • UV detection at 280 nm
  • Budget friendly
  • Compact size, 54x33x30 cm
  • CFR Title 21 Part 11 compliant

 

Customer Reviews

Customer review

iCIEF in Pharmaceutics

“iCIEF plays a critical for monitoring charge variants during biopharmaceutical development. The CEInfinite allows us to get a mass readout for the product variants detected by iCIEF, and this is a great help for understanding the chemical nature of the charge variants.

When combining the CEInfinite with high resolution Orbitrap MS, detailed insight into product variants and product stability can be achieved.

In short, iCIEF MS using the CEInfinite is a very powerful characterisation tool in biopharmaceutical development.”

Customer review

iCIEF-MS for Proteofroms

"The CEInfinite enables direct coupling of iCIEF to mass spectrometry, which is a powerful tool for the characterisation of proteoforms on the intact level.

The obtained high resolution mass spectra are of excellent quality - For me a surprisingly high quality even for intact mAbs although we use generic separation methods (standard ampholytes)."

Prof. Dr. Christian Neusüß, Hochschule Aalen

Customer review

Quick and Easy iCIEF

"CEInfinite iCIEF instrument enables us to verify easily and quickly the behavior of the pI markers we have proposed.

The operation with the instrument is easy and the time for the separation in the order of minutes, while the same focusing task performed in the classical CE capillary equipment with pressure mobilization took hours."

Read his article: CE determination of the thermodynamic pKa...

Request a quotation

Request a quotation for your selection of laboratory instruments, reagents, kits or consumables. 

Do you want to know what we do with your data from this form? Then read our privacy statement.

Contact information

+31 30 6880771
support@isogen-lifescience.com

Our office

Veldzigt 2A
3454 PW De Meern

ISOgen office