icIEF Updates: services, kits, publications and more!
icIEF Platform for FDA regulations: What you see is what you collect
Does the fraction represent the icIEF-identified variant? Our High Yield Fractionation icIEF-Prep responds this with scientific certainty. For the first time, focused charge isoforms can be directly eluted from the separation capillary through nano-flow mobilization control.
- Direct collection of the icIEF peaks of interest.
- No need for indirect orthogonal platforms.
- No more uncertainty surrounding the identity of preparative fractions.
- Unequivocal correlation: “It is what it is.” vs. the assumption-based validation pI comparison e.g. IEX.
Secure Your Method Development — AESlyes as Backup Plan
Are you developing a new method? Make sure to have a backup plan in case you don’t get your Pharmalyte or Servalyte delivered.
- If you wish to learn more visit our website.
- We are happy to consult you with making the right choice. Book an appointment with us for further support.
NEW Publication: icIEF technology for in-depth biopharmaceutical characterization
Key icIEF user
"We thank Dr. David A. Michels and Dr. Feng Yang from Genentech, Dr. Bo Yan from Beam Therapeutics and Professor Janusz Pawliszyn from University of Waterloo for sharing their great experiences and sharing their great insights on the use of the Traditional icIEF and our Next Generation icIEF Solutions" - Isogen Life Science Team.
Key learnings:
- Redefine icIEF Analytical methodologies broadening their applications:
- Critical reagents.
- Capillary coatings for advanced icIEF fractionation.
- Cutting-edge icIEF-MS online coupling.
- Novel applications for protein bio-interactions.
- How to mitigate challenges and setbacks during drug development: icIEF characterizes complex therapeutic proteins.
- Book an appointment with us for further support
Tao Bo, et al. (2025). "Recent Development of icIEF technology for in-depth biopharmaceutical characterization. Trends in Analytical Chemistry 187
New! Minimise the use of additives with our dedicated icIEF Assay Kits
Our new icIEF assay kits are based on reliable hydrophobic cross-linked silicone coating cartridge.
New! Avidity Characterization Services for Antibody Engineering
Cell-antibody avidity matters in Antibody Engineering: We help you to improve your drug development process by determining the potency and specificity of the validated target.
|
