Next Generation iCIEF

CEInfinite Imaged Capillary Isoelectric Focusing (iCIEF) Solutions

Isogen Life Science is the exclusive distributor of the CEInfinite Imaged Capillary Isoelectric Focusing (iCIEF) product line from AES (Advanced Electrophoresis Solutions Ltd). 

CEInfinite Solutions 

Since 2004 our company has been the Total CIEF Solution Provider for any (i)CIEF assays, supporting and delivering the Total CIEF Solutions to the European market.

For Capillary Electrophoresis (CE) Solutions, we offer the CAPEL CE instruments. covering a complete iCIEF and CE Solutions.

The CEInfinite is a new generation WCTID CIEF system, standard equipped with a high sensitivity CMOS imaging sensor and powerful deep UV LED light source.

CEInfinite dramatically increases the scan rate over 100 times compared to any other imaging time-resolved CIEF systems.

It enables the study of fast dynamic processes more accurately, empowering Taylor dispersion, rapid measurement of protein hydrodynamic radius, and protein interaction studies.

Furthermore, it is the only WCTID CIEF system that enables you to perform direct coupling to MS for in-depth characterization studies and high-resolution iCIEF fractionation for peptide mapping, SPR, and biological assays.

CEInfinite iCIEF Solutions

  • Faster method development, higher detection sensitivity, better reliability and higher analytical throughput
  • Automated high-resolution fractionation
  • iCIEF-MS, coupling with mass spectrometry  
  • Method development services - we can perform your method development of any (i)CIEF assays
  • High resolution fractionation services. We can fractionise your samples  
  • A comprehensive portfolio of carrier ampholytes, pI markers, cartridges and solutions for any i(CIEF) assay.

Receive a Special Package Deal for:

  • Replacement of current icIEF
  • Placement of a new icIEF-Prep instrument

The special package will depend on your needs!* Do you need extra consumables? Maintenance contract? Let us know which package you would like and we can discuss about it. 

*Valid until the 31st March 2024.


Customer Reviews

Customer review: iCIEF in Pharmaceutics

"iCIEF plays a critical for monitoring charge variants during biopharmaceutical development. The CEInfinite allows us to get a mass readout for the product variants detected by iCIEF, and this is a great help for understanding the chemical nature of the charge variants.

When combining the CEInfinite with high resolution Orbitrap MS, detailed insight into product variants and product stability can be achieved.

In short, iCIEF MS using the CEInfinite is a very powerful characterisation tool in biopharmaceutical development.”

Dan Bach Krinstensen (PhD - Principal Scientist)

iCIEF-MS for Proteofroms

"The CEInfinite enables direct coupling of iCIEF to mass spectrometry, which is a powerful tool for the characterisation of proteoforms on the intact level.
The obtained high resolution mass spectra are of excellent quality - For me a surprisingly high quality even for intact mAbs although we use generic separation methods (standard ampholytes)."

Prof. Dr. Christian Neusüß (Hochschule Aelan)

Quick and Easy iCIEF

"CEInfinite iCIEF instrument enables us to verify easily and quickly the behavior of the pI markers we have proposed.

The operation with the instrument is easy and the time for the separation in the order of minutes, while the same focusing task performed in the classical CE capillary equipment with pressure mobilization took hours."

Professor Bohuslav Gas (Charles University, Faculty of Science)

Read his article: CE determination of the thermodynamic pKa

Request a quotation

Request a quotation for your selection of laboratory instruments, reagents, kits or consumables. We will get back to you via mail or phone in no more than 24 hours. Promised!

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Contact information

+31 30 6880771

Our office

Veldzigt 2A
3454 PW De Meern

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