CEInfinite iCIEF Instruments
Fast and in-depth characterization under a variety of different conditions including formulation and stability studies.
Our CEInfinite is a next generation cIEF system based on a Whole Column Time-resolved Imaging Detection (WCTID). It is standard equipped with a high sensitivity CMOS imaging sensor and powerful deep UV LED light source that gives an increased scan rate over 100-fold compared to any other (i)cIEF system on the market.
The icIEF-Analytical simplifies the protein charge analysis and provides the highest resolution separation. The icIEF fractionation and icIEF-MS modes allow you to characterize the post-translational modifications (PTMs), antibody-drug ratio (DAR), (im)purity, and chemical degradation underlying each protein charge isomer. The fractionated fractions can be used for your formulation and stability studies, such as peptide mapping, amino acid sequencing & composition, amino- & carboxy-terminal amino acids determination, disulfide bridge assessment, glycosylation & glycan characterization, binding studies (SPR, ELISA,..), potency studies and other biological assays
- Analytical profiling, Method Transfer - Existing CIEF methods
- Your Advantages - the use of CEInfinite Instrument
- Whole Column Time-resolved Imaging Detection (WCID) Technology - High Resolution Separation
- CEInfinite icIEF High Resolution - High Yield Fractionation
- CEInfinite icIEF-MS
- Next Generation Biotherapeutics
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