Capillary Electrophoresis Instruments

Isogen LifescienceProductsInstrumentsCapillary Electrophoresis AnalysersCAPEL Capillary Electrophoresis Instruments

CAPEL Capillary Electrophoresis Instruments

The CAPEL Capillary Electrophoresis (CE) instruments are robust, compact and well design to be used as Dedicated Analysers for several dedicated solutions in the fields of Biopharma, Environmental Analysis, Chemical Industry, Food Testing, Animal feeding and Veterinary.

Besides these dedicated solutions, you can use our CAPEL CE instruments for developing your own specific assay(s) based on capillary zone electrophoresis (CZE), capillary gel electrophoresis (CGE), capillary isoelectric focusing (CIEF), micellar electrokinetic chromatography (MEKC), CE-SDS and so on.

As being Total Solution Provider for CIEF and CE Solutions, we can help you with developing your assays. We will provide you the best services that you need.

Contact us for a demo opportunity!

Other technologies comparison: Chromatography, Colorimetric and Titration, CAPEL CE Analysers 

  • Robustness: well developed and highly dedicated analytical protocols (SOPs)
  • CE technology user-friendly for operation: Simple sample preparation; filter and dilute the sample only.
  • Shorter analysis time because of a faster running time
  • Less labour intensive
  • Low analysis costs
  • Low maintenance costs

 

 

 

Contact us for a demo opportunity!

CAPEL-105M R&D System

The CAPEL-105M R&D system is a dedicated R&D analyser for several dedicated assays in the fields of Biopharma, Environmental Analysis, Chemical Industry, Food Testing, Animal feeding, and Veterinary 

Achieve the Highest sensitive UV detection: ppb level

The CAPEL-105M R&D system is user-friendly for operation and therefore also ideal to be used as a simple CE tool for education purposes to get familiar with Capillary Electrophoresis technology.

Furthermore, you can use the CAPEL-105M R&D system as a versatile analytical tool for dedicated analytical protocols (SOPs) for several fields of markets and for the development of assays based on CZE, CGE, CE-SDS, MEKC, CIEF, and so on.

CAPEL 105M

Why is it the ideal system for you research? Discover more about its benefits!

  • Low running costs - simply use distilled water
  • Avoid any cross contamination thanks to its unique injection mode design
  • User friendly cassette design and operation
  • Save time: Exchange of cassettes in <1 min
  • Save space: Small bench spare
  • Low analysis and running costs
  • Low recycling waste cost

As being Total Solution Provider for CIEF and CE Solutions, we can you help out with the development of your CE assays. Let's work together!

Download the CAPEL-105M Brochure
Ask your questions or request a quote

Customer review

Customer review on CAPEL-105M:

"With the CAPEL CE you can analyse anions, cations, hormones, vitamins, proteins, organic and inorganic acids.

We mainly analyse the salivary ions and release of calcium ions from hydroxyapatite fronds after a short acid attack. Furthermore we also determine the uric acid in saliva.

We have been in possession of two CAPEL CE machines for over a year and we are very satisfied with these machines, the software is easy to use".

Ing Kamran Nazmi ACTA, the Netherlands

CAPEL-205 Routine Analyser

The CAPEL-205M Routine Analyser is a dedicated analyser for several dedicated assays in the fields of Biopharma, Environmental Analysis, Chemical Industry, Food Testing, Animal feeding and Veterinary.

The CAPEL-205M Routine Analyser can also be used as a simple CE tool for education purpose to get familiar with Capillary Electrophoresis technology.

Discover its main benefits

  • Save running and analysis costs - use simply distilled water
  • Avoid any cross contamination: Unique injection mode design
  • Streaming Potential (SP) control to increase migration time and peak area stability (optional)
  • User friendly cassette design and operation
  • Save time: Exchange of cassettes in <1min. 
  • Save space: Small bench spare
  • Low recycling waste costs
CAPEL-205

 

 

Do you want to have more information about the CAPEL-205M?

You can have a look and download at the brochure here!

Do you need help with developing your assays? We will provide you the best services that you need.

Request a quote now 

It provides you:

  • Routinely high sample throughput: Extended autosampler capacity up to 59 positions
  • No evaporation of the sample and/or contamination: Integrated vials caps removal; all solutions are kept in the autosampler capped.
  • Higher separation efficiency and shorter analysis time: A broader High Voltage block up to +/- 30 kV.
  • Increased migration time and peak area stability thanks to the streaming Potential (SP) control feature
  • Highest sensitive UV detection (ppb level)
  • Highly dedicated analytical protocols (SOPs) for several fields of markets

Customer review

Customer review on CAPEL-205

"With the CAPEL CE you can analyse anions, cations, hormones, vitamins, proteins, organic and inorganic acids.

We mainly analyse the salivary ions and release of calcium ions from hydroxyapatite fronds after a short acid attack. Furthermore we also determine the uric acid in saliva.

We have been in possession of two CAPEL CE machines for over a year and we are very satisfied with these machines, the software is easy to use"

Ing Kamran Nazmi ACTA, the Netherlands

Streaming Potential Control Feature

In capillary electrophoresis (CE) is proper conditioning of the capillary one of utmost importance for run-to-run reproducibility of migration times and peak areas of the analytes. This is accomplished by rinsing the capillary. For accessing to the quality of the rinsing procedure we propose to measure a streaming potential (SP), which is a phenomenon that arises between the ends of a fused silica capillary when an electrolyte is pressed through it.

After a new capillary is thoroughly rinsed, a so-called exemplary SP value is saved in a capillary certificate. Later during the sequence of analyses, SP is automatically measured every time after rinsing and is compared with the exemplary value. This unique SP Control feature is optional and can be implemented in the CAPEL-205 Routine Analyser

To learn more about this SP control feature, please review SP Run-to-Run Reproducibility in CE or contact us for further support.

Capillary Electrophoresis Applications

The CAPEL Capillary Electrophoresis (CE) instruments are robust, compact, and well design to be used as Dedicated Analysers for several dedicated solutions in the fields of:

Biopharma 

The CAPEL CE instruments can be used use a versatile Analytical Tool for developing assays in BioPharma that are based on capillary zone electrophoresis (CZE), capillary gel electrophoresis (CGE), capillary isoelectric focusing (CIEF), micellar electrokinetic chromatography (MEKC) and CE-SDS.

All assays that are described in the monographs or general chapters from pharmacopoeias can be executed on the CAPEL CE instruments. Here below you find a selection of several Biopharma applications.

Determination of proteins concentrations and their molecular weights

Compared with protein separation with SDS-Page, using our method give you severalbenefits:

  • Full automatization
  • Direct protein quantification
  • Absence of coloring
  • Short analysis time
  • Low analysis cost

 

 

 

 

 

 

Download Application Note

 

Determination of product-related impurities in recombinant therapeutic monoclonal antibodies

The method is based on Capillary Gel Electrophoresis and executed according to the USP129 and CH.P 3127. It is also possible to run CE-SDS on the CAPEL-205 Routine Analyser.

 

 

 

 

Download Application Note

 

Determination of aprotinin impurities in aprotinin and aprotinin concentrated solution

The method is based on Capillary Zone Electrophoresis and executed according to the EP monographs 0579 and 0580.

 

 

 

 

 

 

Download Application Note

 

QC and Process (Fermentation Control) 

Accurate analysis of fermentation liquid for the presence of inorganic anions, or cations, or organic acids can be of utmost importance to ensure the correct way of the whole  process.

For example, the elevated values of acetic acid can indicate certain deviations in the technology of fermentation, phosphates are important for the microorganism’s vitality and so on.

Our analytical protocol allows you to detect the target compounds in a fermentation liquid in all kinds of fields (BioPharma, Food Industry and so on).

 

 

 

 

 

Download Application Note

Environment Analysis 

The CAPEL CE instruments can be used as Dedicated Analysers for several environmental assays. We have several analytical protocols (SOPs) available for the determination of inorganic cations, organic acids, water chlorination products and several other groups of compounds (herbicides, pesticides and more).

Here below you find a selection of several environmental applications:

Determination of inorganic anions in aqueous matrices 

The method is based on capillary zone electrophoresis and executed according to EPA 6500 and ASTM D6508-10. The method can be used for the analyses of drinking water, wastewater and ground water.

 

 

 

 

 

 

 

 

Download Application Note

 

Determination of chlorate, perchlorate and chlorate ions in drinking and bottled water 

Chlorination is the most widespread way of disinfecting water in the world. Due to high toxicity the maximum permitted levels (MPL) are determined in WHO Guidelines for drinking water.

 

 

 

 

 

 

Download Application Note

 

Determination of water-soluble forms of inorganic cations in soils, clays, peat and many more 

The water-soluble forms of inorganic cations, such as ammonium, potassium, calcium, sodium, magnesium, are one of the substantial characteristics in agrochemical, land reclamation and sanitary assessments of soils. During ecological soil monitoring the cation balance is to be controlled for the human activity impact assessment.

 

 

 

 

 

 

Download Application Note

 

 

Chemical Industry 

The CAPEL CE instruments can be used as Dedicated Analysers for several chemical industrial assays. We have several analytical protocols (SOPs) available for the determination of inorganic cations, inorganic anions, organic acids and so on.

Here below you find a selection of several chemical industrial applications.

 

Determination of acetic acid (acetate anions) in natural, drinking and wastewater 

The method is based on the sample filtration and dilution. Measurement is done with  indirect anions detection at 266 nm.

Download Application Note

 

Determination of inorganic anions and organic acids from traces of corrosion 

Traces of corrosion are taken from the metal surface and extracted in water (a corrosion study (UN project).

Ask your questions

 

 

Determination of Inorganic cations in wastewater from industrial region 

Our analytical protocol allows you to detect the target compounds in wastewater.

Ask your questions

Food Testing

The CAPEL CE instruments can be used as Dedicated Analysers for several food assays. We have several analytical protocols (SOPs) available for the determination of inorganic cations, inorganic anions, organic acids and so on.

Here below you find a selection of several food applications:

 

Determination of synthetic amino acids (methionine, threonine and tryptophan) in fodder additives

Our instrument kit allows you to measure the synthetic amino acids. The method is based on CZE with direct UV detection.Furthermore our instrument kit allows you also to determine free lysine and methionine hydroxy analogue (HMTBa) in fodder additives.

 

 

 

 

 

 

 

Download Application Note

 

Identification and determination of synthetic dyes in soft and alcoholic drinks

Our method allows you to identify and determine several synthetic dyes. These includes Tartrazine, Sunset Yellow FCF, Carmoisine, Amaranth, Ponceau 4R, Erythrosine, Red 2G, Allure Red AC, Patent Blue V, Indigotine, Brilliant Blue FCF, Green C and Brilliant Black BN.

 

 

 

 

 

Download Application Note

 

Determination of D- and L-isomers of tartaric and malic acids in wines, wine materials and food additives

Our methods allows you to determine D- and L-isoforms of tartaric and malic acids in all types of wines, wine materials, and special food additives.

 

 

 

 

 

 

Download Application Note

Animal feeding and Veterinary 

The CAPEL CE instruments can be used as Dedicated Analysers for several food assays. We have several analytical protocols (SOPs) available for the determination of inorganic cations, inorganic anions, organic acids and so on.

Here below you find a selection of several applications.

Determination of anions in feed stuffs, compound feed and feed raw materials

Our method allows you to measure water-soluble chloride, nitrate, phosphate and sulphate in all types of feed stuffs, compound feeds, fodders, premixes, fodder additives and feed raw materials (from plant, animal and mineral origin).

 

 

 

 

 

 

Download Application Note

 

Determination of whey proteins in milk samples by CGE

Our method allows you to determine whey proteins in milk samples. Various ofvarious β-lactoglobulin isoforms can be determined in a short time.

 

 

 

 

 

 

Download Application Note

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