WHOLE COLUMN – IMAGING CAPILLARY ISO ELECTRIC FOCUSSING (WC-ICIEF)
The CEInfinite instrument is a new generation Whole Column Imaging CIEF system:
The CEInfinite overcomes low analytical throughput and difficult method development associated with for instance IEX-LC or traditional CE. With a high sensitivity CMOS imaging sensor and powerful deep UV LED light source, CEInfinite dramatically increases the scan rate over 100 times compared to any other imaging CIEF system. An increased scan rate allows study of fast dynamic processes more accurately, empowering even Taylor dispersion measurement of protein hydrodynamic radius, protein interaction studies. The combination of the patented cartridge and fast scanning rate of the camera also allows for direct coupling to MS to analyse each isomer and even allows for high resolution CIEF fractionation for further studies like peptide mapping, SPR and biological assys.