CLARIOstar plate reader

CLARIOstar plate reader: any wavelength, any bandwidth, any assay

The CLARIOstar is our high-end plate reader which combines flexibility with the best sensitivity possible. Due to its Linear Variable Filter (LVF) monochromators and z-focal height adjustment, the CLARIOstar is the ideal reader for a lab with a big diversity in assays or for assay development and cell based-assays. The bandwidth can be set from 8 to 100 nm, which provides optimal felxibility to set the reader from high specific detection to optimal sensitive detection. Are you looking for a reader that is flexible, sensitive and on top easy to use? Then the CLARIOstar Plus is perfect for you! 

The CLARIOstar plate reader is suitable for a broad range of applications such as assay development, fast or enzyme kinetics, screening, protein detection and DNA/RNA quantification. The detection technologies are also diverse: UV-Vis absorption, Fluorescence (FI, FRET, TR-FRET, polarisation), Luminescence (LUM, NanoBRET, BRET) and AphaScreen/LISA/Plex. This BMG plate reader is ideal for analysing living cells, as the CLARIOstar consist of a self-regulating O2 and CO2 gas regulation system and an incubator to keep the samples at the perfect temperature. Additionally, the gas ramps can easily reduce the O2 from ambient to hypoxic. 

Thanks to the special Enhanced Dynamic Range (EDR) Technology, each sample is automatically measured with the optimum sensitivity guide setting. As a result, it is no longer necessary to set a gain in advance. The EDR technology provides great ease of use with kinetic assays, where the end signal is still unknown or when there is a big diversity in signal strength within a plate.

The CLARIOstar can easily change from top to bottom analysis. It consists of a well surface scan for non-homogeneous sample and is able to analyse a maximum of 1536 wells simultaneous. Another possible way to measure non-homogeneous well contents is the unique orbital and spiral averaging feature. Using these modes, the plate reader takes several measurements for each well on a defined orbit, collects the data and calculates an average. For real-time analysis the reagent injection can be used for addition of stimulus or inhibitors with 100 measurements per second.

Benefits of the CLARIOstar

  • High flexibility and sensitivity - LVF monochromator
  • Time saving – 1536 wells simultaneous
  • Living cell analysis – gas and temperature control

Download CLARIOstar Plus-Brochure

Download the Verifying SPARCL performance Application Note

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