CLARIOstar

Broad range of applications

The CLARIOstar plate reader is suitable for a broad range of applications such as assay development, fast or enzyme kinetics, screening, protein detection and DNA/RNA quantification. The detection technologies are also diverse: UV-Vis absorption, Fluorescence (FI, FRET, TR-FRET, polarisation), Luminescence (LUM, NanoBRET, BRET) and AphaScreen/LISA/Plex. This BMG plate reader is ideal for analysing living cells, as the CLARIOstar consist of a self-regulating O₂ and CO₂ gas regulation system and an incubator to keep the samples at the perfect temperature. Additionally, the gas ramps can easily reduce the O₂ from ambient to hypoxic. 

Enhanced Dynamic Range Technology

Thanks to the special Enhanced Dynamic Range (EDR) Technology, each sample is automatically measured with the optimum sensitivity guide setting. As a result, it is no longer necessary to set a gain in advance. The EDR technology provides great ease of use with kinetic assays, where the end signal is still unknown or when there is a big diversity in signal strength within a plate.

Specifications and modes

The CLARIOstar can easily change from top to bottom analysis. It consists of a well surface scan for non-homogeneous sample and is able to analyse a maximum of 1536 wells simultaneous. Another possible way to measure non-homogeneous well contents is the unique orbital and spiral averaging feature. Using these modes, the plate reader takes several measurements for each well on a defined orbit, collects the data and calculates an average. For real-time analysis the reagent injection can be used for addition of stimulus or inhibitors with 100 measurements per second.