Event

In the competitive field of antibody-drug conjugates (ADCs), mastering charge heterogeneity is critical but challenging compared to their monoclonal antibody precursors. Join our webinar to discover how native icIEF-MS can reveal in-depth information that often eludes conventional methods.

• August 14 at 10:00 AM EST (16:00h CEST!)

• Registration link: Sign up here!
• Speaker: Matt Courtney

Learning Objectives:

1. Review the key differences between imaged capillary isoelectric focusing (icIEF) and ion exchange chromatography (IEX) for characterizing ADC charge heterogeneity.
2. Stay informed about emerging icIEF-MS technologies for the comprehensive characterization of ADCs under native conditions.
3. Understand how native icIEF-MS provides rapid feedback on the critical quality attributes of different ADC charge isomers, including post-translational modifications (PTMs), drug-to-antibody ratios (DAR), and more.