RNases

Protect your RNA with confidence

RNases are one of the biggest challenges in RNA workflows. These highly stable enzymes are everywhere and can rapidly degrade RNA, compromising applications such as RT-qPCR, RNA sequencing, and transcriptomics.

RNase inhibitors help prevent RNA degradation by blocking RNase activity. However, many conventional inhibitors lose performance under demanding conditions, such as elevated temperatures or oxidative environments.

DB Ultima H RNase Inhibitor is a highly engineered, human-origin inhibitor designed for reliable RNA protection. It remains active at high temperatures, including reverse transcription steps up to 55°C, where standard inhibitors may fail.

With strong thermal stability, oxidative resistance, and excellent storage performance, DB Ultima H gives researchers peace of mind: add it to your reaction and trust that your RNA remains protected.

Ideal for: RT-qPCR, reverse transcription, RNA-Seq, and other RNA-based workflows.

The most potent and stable inhibitor on the market

  • Thermal Stability: The only protein inhibitor stable at or above 55°C.
  • High Potency: Highest possible inhibition of human RNases. Also inhibits other eukaryotic and E. coli RNases.
  • Extraordinary Resilience: Stable for months at room temperature. 
  • Direct RT-PCR ready: Even higher activity than human RNase inhibitor in human tissues. Higher temperatures ensure increased yields and sensitivity.

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support@isogen-lifescience.com

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